Key Benefits

• Well tolerated, few side effects
  
  
• Undiminished anti-microbial activity
  
  
• "Gold standard" in anaerobic coverage
  
  
• Convenient dosing
  
  
• Rapidly bactericidal, good tissue penetration
  
  
• Anti-microbial efficacy which remains undiminished over time
  
  
• Long t½, active metabolite extending duration of action

Indications

• Invasive intestinal amoebiasis
  
  
• Extra intestinal amoebiasis
  
  
• Bacterial vaginosis
  
  
• Urogenital trichomoniasis
  
  
• Acute ulcerative gingivitis/acute dental infections
  
  
• Leg ulcers and pressure sores
  
  
  
  

Indications

• Treatment of sensitive protozoal infections:
  - acute invasive amoebic dysentery
  - hepatic amoebiasis
  - giardiasis
  - Trichomoniasis
  
  
• Prophylaxis and treatment of infections caused by susceptible anaerobic bacteria including:
  - bacterial vaginosis, aspiration pneumonia and lung abscess
  - acute ulcerative gingivitis and other periodontal infections
  - peritonitis and intra-abdominal sepsis, post-operative
    wound infections where appropriate